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[DOI] [Google Scholar] 263.Lee E., Padgett B
The frequency of injections may vary based on your individual needs and health goals
The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed
This peritendinous injection approach can reduce inflammation while avoiding direct intratendinous administration, which carries higher complication potential
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