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However, these applications are currently in the preclinical exploration stage, and large-scale clinical studies have yet to be conducted

10.1038/s41416-018-0327-z 45 GoebelG.BergerR.StrasakA

Furthermore, we generate 3D structural model of SARS-CoV, Khosta-2 and Rs4081 S proteins with AlphaFold server 43 , and a structural comparison of the S proteins of suggests that their putative S1/S2 cleavage sites look a similar conformation and may be susceptible to elastase (Fig