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These proteins could potentially support the absorption of glutathione precursors, such as cysteine, which is crucial for glutathione synthesis

Specific alterations include reductions in Prevotella , Coprococcus , and Veillonellaceae , alongside overgrowth of Desulfovibrio (positively correlated with Autism spectrum disorder severity) (258), Sutterella , Ruminococcus , Clostridium , Megamonas , and Candida ( 259, 260), accompanied by an elevated Firmicutes/Bacteroidetes ratio (255)

To determine whether these changes in gene and protein expression led to a functional disruption of the tight junction, immunofluorescence against claudin-5 was performed, demonstrating staining localized to the cell membrane of basal cells

Rossignol R, Letellier T, Malgat M, et al (2000) Tissue variation in the control of oxidative phosphorylation: implications for mitochondrial diseases