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Entre los diagnsticos diferenciales de esta entidad se incluye principalmente al sndrome de Peutz-Jeghers (SPJ), la enfermedad de Addison, el melanoma24, el sndrome de LAMB o el complejo de Carney (lntigos en piel y mucosa bucal, mixomas auriculares y mucocutneos, y mltiples nevos azules)25, sndrome de LEOPARD (lntigos, anormalidades electrocardiogrficas, hipertelorismo ocular, estenosis pulmonar, anormalidades de genitales, retraso del crecimiento y sordera)26, entre otras entidades, por lo que es necesario realizar un examen detallado para diferenciarlo de estas27

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10th ed.Washington, DC: Departments of Agriculture

Cardiovascular safety is another distinction: phentermine increases heart rate and blood pressure in most users, while GLP-1 medications have demonstrated cardiovascular benefits in clinical trials, including reduced risk of heart attack and stroke in people with type 2 diabetes