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Dite TA, Langendorf CG, Hoque A, Galic S, Rebello RJ, Ovens AJ, Lindqvist LM, Ngoei KRW, Ling NXY, Furic L, Kemp BE, Scott JW, Oakhill JS, Peter S, MacKillop M (2018) AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 the and the The atomic coordinates and structure factors (code 6BX6) have been deposited in the Protein Data Bank

The subsequent pathophysiologic mechanisms can be summarized as acute tubular apoptosis, oxidative stress, inflammation, microcirculatory dysfunction, vascular barrier function disorder, local hypoxia, and tissue edema (84)