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symptoms occur during the neonatal period, infancy, or early childhood, as well as during adolescence and adulthood

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Didato explains why patients can sleep 7-8 hours and still wake exhausted covering sleep architecture disruption, growth hormone Low-Dose Naltrexone (LDN) Immune Modulation Therapy Low-dose naltrexone (1.5-4.5mg) modulates the immune system through transient opioid receptor blockade, upregulating endorphin production and enhancing immune surveillance