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Intranasal administration facilitates drugs bypassing the blood-brain barrier (BBB) via the olfactory nasal neuroepithelium

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Thus, considering BPC 157/Parkinsons disease/Alzheimers disease, BPC 157 therapy was effective in Parkinsons disease models, and it counteracted parkinsonogenic neurotoxin MPTP-induced tremor, rigor, akinesia, and gastric lesions and counteracted mortality in mice, reserpine-induced akinesia, catalepsy, hypothermia, and catalepsy induced by neuroleptics or NOS-blocker L-NAME application [198,199,200]

L., Pasch, A