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At 5:00 pm, mice were administered with the vehicle (saline), semaglutide (0.5 mg/kg, s.c.), tirzepatide (0.05 mg/kg, s.c.), and retatrutide (0.05 mg/kg, s.c.)

These include orlistat, liraglutide, and semaglutide (NICE TA875 for weight management in adults with obesity), as well as GLP-1 receptor agonists within the framework of NICE NG28 (type 2 diabetes management)

This mechanism is supported by peer-reviewed research, including studies by Khavinson and colleagues published in gerontology journals, confirming its biological effects

Mental health concerns including depression, memory impairment, or alterations in behavior