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[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Nolan J.M., Loskutova E., Howard A., Mulcahy R., Moran R., Stack J., Bolger M., Coen R.F., Dennison J., Akuffo K.O., et al
Tokyo, Japan: Takeda Pharmaceuticals, 130
Brain Fog 101: What It Feels Like And Where It Comes From Brain fog is not a formal medical diagnosis, but it describes a recognizable cluster of symptoms: Trouble focusing or staying on task Slower processing speed or blanking out mid-conversation Word-finding issues or short-term memory lapses Mental fatigue that doesnt match your sleep Irritability, low motivation, or feeling emotionally flat Common contributors include: Chronic stress and high cortisol Poor sleep quality , circadian disruption, or shift work Blood sugar swings and processed diets low in micronutrients Chronic inflammation and oxidative stress Environmental exposures , such as pollutants or mold Post-viral states and other immune challenges Medications or substance use that affect the nervous system Many of these factors increase reactive oxygen species (ROS) and inflammation in the brain
