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The FDA-approved branded formulations have specific BMI cutoffstypically BMI 30 or BMI 27 with weight-related comorbiditiesbut clinical practice increasingly considers metabolic markers, cardiovascular risk profiles, and individual health history beyond the scale

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[6] [8] The pharmacological action of liraglutide involves stimulating insulin secretion in a glucose-dependent manner (which reduces the risk of hypoglycaemia when used alone), suppressing glucagon release, and slowing gastric emptying

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