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RBCs are particularly susceptible to oxidative stress due to the lack of nuclei needed for protein synthesis, the absence of mitochondria capable of supplying NADPH outside of the PPP, and a high iron content that drives Fenton chemistry 8

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Conclusion: Building Resilience Current evidence indicates that detoxification constitutes a continuous, enzyme-mediated metabolic process rather than a sporadic or episodic event

Here are a few tips to manage the most common side effects: Nausea Eat small, bland meals throughout the day instead of large meals