tirzepatide summit trial Effects of on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SURPASS to SURMOUNT: The Tirzepatide

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Outcomes The outcome of interest, intestinal obstruction, was identified using ICD-10 diagnosis codes, including obstruction of duodenum (ICD K31.5), paralytic ileus (ICD K56.0), ileus (ICD K56.7), and other specified types of intestinal obstruction (ICD K56.4, K56.6) [15, 16]

Ozempic, a prescription drug that contains semaglutide, a GLP-1 receptor agonist originally developed to manage type 2 diabetes

Semaglutide typically produces more dramatic total weight loss but includes muscle and water loss along with fat, whereas AOD-9604 more selectively targets fat tissue