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Alterations in trkB mRNA in the human prefrontal cortex throughout the lifespan

She holds the following professional credentials and advanced training: Board Certified Family Nurse Practitioner (FNP-BC) American Board Anti-Aging Health Practitioner Advanced Certification in Functional & Integrative Medicine IV Nutritional Therapy & Bio-molecular Treatment Protocols Bio-Identical Hormone Replacement Therapy (BHRT) Medical Weight Management & Metabolic Optimization Regenerative & Aesthetic Medicine (including PRP and micro-needling) Her clinical philosophy emphasizes root-cause evaluation, preventive medicine, and individualized care strategies designed to improve vitality, balance hormones, enhance metabolic function, and support healthy aging

doi: 10.1038/s12276-022-00863-4 37 LevineAJ

Autophagy defects lead to the accumulation of depolarized mitochondria and proteins and induce the release of inflammatory body activator (ROS or mitochondrial DNA) [92, 93]