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Other studies have confirmed that HO-1 obstructs the initiation of inflammation and ROS by directly regulating the activation of immune cells, including the antigen-presenting cells (APCs) and lymphocytes [41,42,43]
Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models
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Neuronal NO synthase (nNOS) and endothelial NO synthase (eNOS) are constitutive NO synthases, and responsible for the continuous basal release of NO
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