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As presented in Table 2, the 90% CI for the ratio of IcoSema/semaglutide was fully contained within the range of 80%125% for total exposure after single dose (AUC 0 t ,SD,Semaglutide ), suggesting similar relative bioavailability of semaglutide following IcoSema administration and semaglutide administration alone

However, caution is warranted as inhibiting eryptosis could potentially interfere with the apoptosis of tumor cells, which might diminish the effectiveness of cytostatic therapies

Rebound hypersecretion after inhibition of gastric acid secretion

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