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In addition, systematic reviews and meta-analyses of randomized controlled trials report improvements in cardiac systolic and diastolic function in patients with type 2 diabetes, as well as reductions in infarct size after myocardial infarction [163]

Additionally, the caloric deficit created by reduced food intake means less energy is available for thermogenesis, the process by which the body produces heat

Initiation of second line therapy with OCA and/or fibrates were recorded

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