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Additionally, FGF7 and its receptor fibroblast growth factor receptor-2 (FGFR2), along with its various isoforms, are significantly linked to the progression risk in breast cancer cell lines [18]

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Other studies have confirmed that HO-1 obstructs the initiation of inflammation and ROS by directly regulating the activation of immune cells, including the antigen-presenting cells (APCs) and lymphocytes [41,42,43]

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