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Oral semaglutide incorporates SNAC, which facilitates transcellular absorption via the gastric mucosa through various mechanisms including increased lipophilicity, transforming semaglutide to a more permeable monomeric form, and local elevation of pH and the resultant pepsin-inhibiting effect [18]

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Step 3: Prepare for Potential Side Effects Since an early dose can cause a peak in medication levels, be proactive