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Int J Rheumatic Dis

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Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of lipids

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Figure 5: Proposed mechanism of Graves' disease pathogenesis

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TREM-1 has synergistic effects with cell surface pattern recognition receptors (PRRs) such as toll-like- and NOD-like- receptors to accelerate the production of proinflammatory cytokines such as TNF- and IL-1

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