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On univariate analysis of GWAS SNPs they also identified extremely strong association signals (p = 10 -78 to 10 -13 ) at SNPs in and near VKORC1 and CYP2C9

We also highlight potential issues and challenges encountered in practical applications, including the determination of multi-factorial weightings, requirements for data quality and quantity, establishment of unified predictive indicators and standards, enhancement of model generalizability, and interpretability of prediction outcomes