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The Role of Melanin in Skin Pigmentation Melanin serves as the body's natural defense mechanism against harmful ultraviolet radiation, but when melanin production becomes dysregulated, it leads to visible pigmentation problems

10.1073/pnas.2006828117 51 LiS.CaoP.ChenT.DingC

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Moreover, another study documented that 400 mg/d riboflavin supplementation during 3 months had the same favorable effects as 500 mg/day sodium valproate on patients with migraine (36)