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Dalton TP, Dieter MZ, Yang Y, Shertzer HG, Nebert DW (2000) Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

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NICE guidance (NG49) and NHS resources emphasise these interventions as first-line management, with no specific supplements currently recommended as standard treatment for NAFLD

This review systematically elucidates the molecular mechanisms of ferroptosis, its interplay with MM pathogenesis, and pharmacologic strategies leveraging ferroptosis modulation for MM intervention