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Given that retatrutide is not yet approved for clinical use in the UK, the most appropriate course of action for any woman interested in this treatment is to speak with her GP or a specialist in a Tier 3 or Tier 4 weight management service, or an endocrinology or diabetes team

The term denatured protein refers to a protein compound (made up of several amino acids connected by peptide bonds) whose spatial arrangement is no longer natural

The authors hypothesized that the physiological significance of DHAR activity depends on the ascorbate pool size and that DHARs are required only at high levels of ascorbate