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In the kidneys, GLP-1RAs lower urea, creatinine, and pro-inflammatory cytokines via AMPK-dependent pathways, supporting renal function during sepsis-induced acute kidney injury

Progress on this front was incremental and took many twists and turns

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However, these patches do not contain actual GLP-1 receptor agonists like semaglutide (found in Ozempic and Wegovy) or tirzepatide (found in Mounjaro and Zepbound)