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However, a dysregulated increase in the level of these free radicals, as seen in mitochondrial diseases, can result in oxidative damage by overwhelming the cellular antioxidant defence mechanism, of which glutathione is the principal component [4]

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Since APAP is responsible for nearly half of the cases of acute liver failure in the United States and remains the leading cause for liver transplantation, continued awareness, education and research should be undertaken

In other words, the change acknowledges obesity as a medical factor contributing to chronic illness without yet classifying it as a stand-alone disease for coverage