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This is particularly important if you have a history of gastrointestinal problems, cardiovascular disease, kidney impairment, or if you are pregnant or breastfeeding, as these conditions may influence the safety profile of either medication

The patients started on low doses and increased gradually, reaching the full Wegovy dose over 72 weeks

If sleep problems persist, maintaining a sleep diary for 2-3 weeks can help identify patterns and potential triggers

The hypoglycaemic effect of GLP-1RAs is achieved by stimulating insulin secretion in pancreatic cells, suppressing glucagon secretion in pancreatic cells, and slowing gastric emptying