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A daily supplement of 2,500-5,000 mcg of biotin is generally safe, but there is a critical caveat that every patient and prescriber should know about

Nevertheless, the clinical translation of L-citrulline faces significant challenges, which necessitate focused efforts to address three key issues in future research: first, current dosage recommendations are derived predominantly from animal studies, leaving the optimal supplementation dose for human subjects yet to be determined

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Treatment of iatrogenic hypothyroidism is to reduce methimazole/carbimazole dose, if the cat is receiving it, or supplement with levothyroxine (10g/kg/day to 20g/kg/day), which can be adjusted to maintain normal T 4 and TSH