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Use it on the same day each week, at any time of day, with or without food

Nausea typically subsides within 1520 minutes of IV administration

Specific recommendations include: Eat slowly and stop when comfortably satisfied the medication increases satiety, so eating past fullness often triggers nausea Stay well-hydrated with clear fluids throughout the day, taking small sips rather than large amounts at once Choose bland, easily digestible foods such as crackers, toast, rice, bananas, and lean proteins during symptomatic periods Avoid lying down immediately after eating remain upright for at least 23 hours after meals Identify and avoid personal trigger foods that consistently worsen symptoms For constipation , which is also common with tirzepatide, strategies include staying well-hydrated, gradually increasing fiber intake as tolerated, maintaining physical activity, and discussing stool softeners with your healthcare provider if needed

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