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Leaving it at room temperature for an extended period will cause the active ingredient to degrade, reducing its effectiveness and potentially compromising its safety

If using a particularly thin gauge needle (31G or smaller), consider using a slightly larger gauge (29G or 28G) for reconstitution, then switching to the finer needle for drawing doses

In clinical trials for Wegovy, fatigue occurred more frequently in patients receiving semaglutide compared to those on placebo

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