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Several phytochemicals, including berberine and other isoquinoline alkaloids, inhibit the assembly and activation of NLRP3, reducing mature pro-inflammatory cytokine release and mitigating neuroinflammation and neuronal loss in PD models ( Beyond immunomodulation, many plant phytoconstituents exert antioxidant and mitochondrial protective effects that are crucial in neurodegeneration

Furthermore, the lawsuit states that the prescribing information for these drugs failed to adequately disclose risks of gastrointestinal issues or offer warnings about developing conditions like gastroparesis

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