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OrganCOtsukaHBhushanSWangZBradleyJTrivediRet alCholine diet and its gut microbe-derived metabolite, Trimethylamine N-Oxide, exacerbate pressure overload-induced heart failure

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Importantly, SANA (200 mg per kg per day) not only promoted weight loss, but also showed increased effectiveness compared to salicylate (200 mg per kg per day) and metformin (300 mg per kg per day) in glycaemic control during the 3-week period studied (Fig