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Control mice received standard chow with saline gavage

PYY levels rise to a plateau at 12h postprandially, with peak levels influenced both by number of calories and by composition of the macronutrient.26 Long-term augmentation of dietary proteins in mice increased plasma levels of PYY, decreased food intake and reduced adiposity

A previous brain magnetic resonance spectroscopy imaging study demonstrated that the levels of GABA and glutamate cycling was abnormal in patients with depression when compared to those in the normal brain (Sanacora et al., 2008)

a yet further aspect provides a host cell or virus comprising one or more expression constructs or expression vectors of the invention