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However, as a result of metal-based NP exposure, the mitochondrial electron-transport chain (METC) would be disrupted, thus resulting in the elevation of intracellular ROS level ( 2 NPs, NADPH oxidase was hyper-activated, and the subsequent increase in ROS generation induced a higher level of oxidative stress (Masoud et al., 2015)
A content analysis was selected to allow for manifest level analyses, where participant language was used in the name of each code, and the final code list (Electronic Supplementary Material [ESM]) became the final list of concepts, without additional levels of interpretation and abstraction
Electron microscopy has shown the presence of desmosomes, melanosomes and neurosecretory granules that is correlated with the expression of markers of epithelial, melanocytic and neuroectodermal in immunohistochemistry: CKAE1/AE3, Melan A, HMB45, protein PS100, SOX10, CD99, CD57 (LEU-7), NSE: (enolase) and synaptophysin