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Two of the six SLGTs are well characterized: (1) SLGT-1with low capacity, located in small intestine and in the renal proximal convoluted tubule responsible for only 10 % of glucose re-absorption and (2) SLGT-2with a high capacity of absorption, in the early proximal convoluted tubule, responsible for the remaining 90 % of glucose reabsorption (Vasilakou et al