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albicans to transform from a symbiotic state to a pathogenic state (Witchley et al., 2019)

Effects on telomere length and cellular health appear to persist for months after completing a cycle, which is why extended off-cycle periods work within the protocol design

These alterations in the tumor ECM induce an increase in its stiffness, typically evaluated using techniques that either require direct contact with the sample (e.g., atomic force microscopy), or measure the tumor mechanical properties in a contact-free manner (e.g., shear wave elastography, magnetic resonance elastography) (Table 3)

[34] Tang L, Jin T, Zeng X, et al