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Phase I pharmacokinetic studies estimate parent-molecule oral bioavailability in the range of 4-16%

The oxidation of compound with t-BuOOH produces the transient selenoxide , which undergoes a spontaneous cyclization to produce the dioxyselenurane isolated compound structure was confirmed by spectroscopic methods and single X-ray crystallography

National Vital Statistics System, Report No

angiotensin IV analogue Sequence (formal name): N-hexanoic-Tyr-Ile-(6) aminohexanoic amide IUPAC name: 6-[(2S,3S)-2-[(2S)-2-hexanamido-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]hexanamide Synonyms: PNB-0408, Hexanoyl-Tyr-Ile-Ahx-NH 2 , MM-201 (older designation) CAS Number: 1401708-83-5 Molecular Formula: C 27 H 44 N 4 O 5 Molecular Weight: 504.66 g/mol Solubility: slightly soluble in DMSO and methanol