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What to Eat After Vomiting

Under the therapeutic concentrations, approximately 60%90% of APAP is metabolized in the liver by glucuronidation and sulfation, with a small part (approximately 5%15%) being metabolized by the cytochrome P450 pathway (CYP450) ( via two pathways to form the toxic intermediate N-acetyl-p-benzoquinone imine (NAPQI) and the non-toxic catechol metabolite 3-hydroxy-APAP (3-OH-APAP) (Figure 1)

While research continues on protected oral formulations, injection remains the gold standard for reliable effects

MH participated in data extraction, writing the manuscript, its rigorous revision several times, and coordinated the flow of the work