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Critically, "Many patients regain two-thirds of their weight when coming off of these medications." These represent "not a quick fix for weight loss" but require "a commitment to regular injections and ongoing monitoring." 4

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Furthermore, investigating specific regions important in reward neurocircuitry, Ex-4 injection into posterior VTA or NAc shell reduces pre-sexual interaction behaviors, and intra-LDTg Ex-4 reduces all phases of sexual interaction behaviors (Vestlund and Jerlhag, 2020a)