This hormone-based approach targets the root biological drivers of appetite and hunger rather than simply stimulating the central nervous system
Were left wondering, How are GLP-1s causing these effects? asks senior author Marc Montminy, MD, PhD, a biochemist, physiologist, and distinguished professor emeritus at Salk
The team also explores mechanical eating, the psychological impact of diet food, and Andreas 13-year metabolic recovery journey
In a polymicrobial model of sepsis induced by cecal ligation and puncture, a GLP-1 analog ameliorated vascular inflammation and oxidative stress by improving endothelial function ( In a cardiac fibrosis model, the GLP-1 analogue liraglutide reduced vascular reactivity, cardiac hypertrophy, fibroblast accumulation, collagen deposition and MCP-1 production ( GLP-1 improved left ventricular function in patients with chronic heart failure and in dogs with dilated cardiomyopathy