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Malignant cells exhibit altered metabolism, heavily relying on glucose via the Warburg effect and producing lactate even in oxygen-poor conditions

ADVERSE EFFECTS Some epidemiologic evidence indicates that long-term use of acetaminophen is associated with an increased risk of renal dysfunction .M Although therapeutic doses of acetaminophen are remarkably nontoxic, the ingestion of 20 to 30 tablets is sufficient to cause life-threatening hepatotoxicity .

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