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Individuals with a history of depression should be closely monitored for any worsening symptoms or new mental health issues

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The American Diabetes Association and USDA Dietary Guidelines recommend focusing on nutrient-dense, high-fiber foods including vegetables, lean proteins, and whole grains to maximize weight loss while on GLP-1 therapy

A 2025 study published in Obesity Medicine found that patients treated by an obesity specialist were 8 times more likely to persist on GLP-1 therapy than those treated in general care settings