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Dectin-1 It is a type II trans-membrane protein receptor (C-type lectin receptors, CLRs), and its structure consists of four parts such as (1) a carbohydrate recognition domain, (2) a single trans-membrane region, (3) a short stalk region, and (4) a cytoplasmic tail consisted of immunoreceptor tyrosine-based activation motif (ITAM) (159161)