A previous CSP analysis using FOXO4 FHD titration of 15 N-labeled p53 TAD showed that significant perturbations two standard deviations above average were mostly observed in residues within the p53 TAD2 region 38
Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris PJ, Thomas CJ, Possemato R, Vander Heiden MG, Papagiannakopoulos T
Once reconstituted from its lyophilised form, the peptide becomes vulnerable to hydrolysis, oxidation, aggregation, and microbial contamination making correct storage, handling, and adherence to sponsor-validated stability data essential for safety
Oxidative stress and DNA damage in untreated first-episode psychosis in adolescents