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N Engl J Med 362(4):329344

Navigating the GLP-1 Wave: A Strategic Guide for Plan Sponsors Pain Point : Theres a lack of clear guidance on how to best incorporate and manage coverage for new and expensive GLP-1 medications into existing health plans

Medications like semaglutide (sold as Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) help people lose significant amounts of weight often 1520% of their body weight over about a year

Chronic oxidative stress can trigger the activation of microglia, leading to the release of pro-inflammatory cytokines and other molecules that can cause damage to neurons and promote neuroinflammation