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To demonstrate specificity of the effect, we sought to rescue the decreased mEPSC frequency by pretreating with pyroglutamate (PGA), the precursor of glutamate that is synthesized downstream of GGT, which is blocked by acivicin (Fig
Diazgranados, N
In this review, we summarize recent advances in our understanding of the molecular mechanisms of NAD + -regulated physiological responses to stresses, the contribution of NAD + deficiency to various diseases via manipulating cellular communication networks and the potential new avenues for therapeutic intervention
Chaperon Peptides A fundamental event in cataract formation is the loss of solubility of crystallin proteins, which are the most abundant proteins in the lens, resulting in aggregate formation
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