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Biochem J 340:309

Sinagra, T., Merlo, S., Spampinato, S

It has a long history of use as a botanical remedy dating back to the fourth century BCE, when ancient Greeks regarded it as a general medicinal herb.1 Since then, it has been used to treat an array of ailments, including but not limited to: Hepatitis Cirrhosis Jaundice Diabetes The active ingredient in milk thistle is silymarin, a group of flavonoids that comprises silybin, silychristin, isosilybin, and silidianin.11 Silymarin is whats known as a free radical scavenger, otherwise known as an antioxidant

It doesn't mess with other hormones, like cortisol or prolactin