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The study provides a new and ideal therapeutic option for diabetic fracture and other musculoskeletal diseases. The study employed the plant-based drug production platform that Daniell has developed over many years, which entails introducing a protein of interest into plant cells, prompting them to begin expressing that gene in their cells, eventually producing that protein in their leaves which can be harvested and used in an oral therapy

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To further identify the specific HDAC isoform that was involved in regulating GLP-1R expression, isoform-specific HDAC inhibitors were used

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