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Weekly dosing proved to be a gamechanger: it maintains sustained GLP-1 receptor stimulation with far fewer injections, leading to broad adoption in diabetes and obesity care

Cells were washed thrice with phosphate-buffered saline and treated with dimethyl sulfoxide or compounds in Dulbecco's modified Eagle medium (high glucose) without fetal bovine serum in the presence of mitomycin C (1 M)

In 537 adults with type 2 diabetes (85% treatment-naive, on stable metformin), the 12mg dose produced HbA1c reductions up to 2.0% and weight loss up to 16.8% at 40 weeks, with no plateau observed

MASLD occurs when fat accumulates in the liver and is now one of the most common liver conditions worldwide