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Going forward, it will be of primary importance to better understand the in vivo metabolic profiles and dynamics in the kidneys and nephron segments of animals and humans, and the investigation of genetic and environmental factors that lead to the development of hypertension by influencing these metabolic processes may help identify any pro-hypertensive regulatory dysfunctions that result from such metabolic abnormalities

A kinetic study of drug elimination: the excretion of paracetamol and its metabolites in man

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The abstracts of the remaining 49 articles were evaluated for relevance