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Journal of Physiology (Paris), 1993, 87(5):313-327

Insert the needle through the stopper and let the water run slowly down the inside wall of the vial do not squirt it directly onto the powder

Factors such as polymer or lipid concentration, phytoconstituent-polymer ratio, fabrication process, and parameters like temperature, pH, stirring speed, and solvent can have an impact on the drug entrapment efficiency (drug loading in nanocarriers)